Scientific Studies

The Science Behind Peptan™

Study 1: Anti-Ageing Effect


Study 1: Anti-Ageing Effect

*The study was conducted on 47 females (aged 35 to 55) at DERMSCAN in Lyon, France.

Study 2: Moisturising Effect


Study 2: Moisturizing Effect

*The study was conducted on 33 females (aged 40 to 59) at SOUKEN in Tokyo, Japan.


The Science Behind Rose Extract

Study 1: Anti-Tyrosinase Ectivity

Study 1: Anti-Tyrosinase Activity

Method

Measured the activity of melanin cells by adding rose petal extract to these cells for six days.

Result

The activity of melanin cells decreased by 43.3%.

Study 2: Anti-Radical Activity

Study 2: Anti-Radical Activity

Method

Measured anti-radical activity by adding rose petal extract to melanin cells for 6 days.

Result

The radical activity increased by 40%.


The Science Behind Royal Jelly

Study 1: Identification of a collagen production-promoting factor from an extract of royal jelly and its possible mechanism.

Method

In this study, the collagen production-promoting activities of several commercially available fatty acids contained in royal jelly were examined.

Result

Royal jelly contained 10H2DA that increased the collagen production in a dose-dependent manner. Furthermore, 10H2DA induced the fibroblast cell line, NHDF, to produce transforming growth factor-beta 1 (TGF-beta 1) which is an important factor for collagen production.

Study 2: Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production.

Method

In this study, the effects of royal jelly and 10H2DA on UVB-induced photoaging were tested by measuring procollagen type I, transforming growth factor (TGF)-β1 and matrix metalloproteinase (MMP)-1 after UVB irradiation.

Result

The UVB-irradiated human skin fibroblasts treated with royal jelly and 10H2DA had increased procollagen type I and TGF-β1 productions. Thus royal jelly may potentially protect the skin from UVB-induced photoaging by enhancing collagen production.


The Science Behind Amla

Study 1: Anti-Cytotoxic Activity

Study 1: Anti-Cytotoxic Activity

Picture A

Untreated Swiss 3T3 mouse fibroblast cells showing cytotoxicity after UV exposure;

Picture B

Swiss 3T3 mouse fibroblast cell treated with 80mcg/ml of β glucogallin showing 90% reduction in cytotoxicity after UV exposure.

Study 2: Anti-Melanogenesis Activity

Study 2: Anti-Melanogenesis Activity

Picture A

Untreated B16F1 mouse melanoma cells showing melanogenesis after UV exposure;

Picture B

B16F1 mouse melanoma cells treated with 80mcg/ml β glucogallin showing 55% reduction in melanogenesis after UV exposure.

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